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The Lab

Disease states

Severe LVH · Preserved EF

Severe concentric LV hypertrophy with preserved reference ejection fraction, impaired relaxation and elevated left-sided filling pressures. This selected nonobstructive phenotype has adequate resting forward flow and systemic blood pressure.

Overview

Select Severe LVH · Preserved EF under Clinical controls → Hemodynamic state. The bold italic live label confirms the active selection. These are the preset’s teaching features; combined disease, rate and interventions can change the resulting numbers.

Severe concentric LV hypertrophy with preserved reference ejection fraction, impaired relaxation and elevated left-sided filling pressures. This selected nonobstructive phenotype has adequate resting forward flow and systemic blood pressure.

At HR 75 bpm and CO 5.25 L/min, the illustrative LV EDV of 112 mL and ESV of 42 mL give EF 62.5%. Preserved EF does not mean normal filling pressure.

Mean PAWP is 22 mmHg and LVEDP is 26 mmHg at reference loading; these are distinct pressure measurements, not interchangeable diagnostic cutoffs.

The schematic has severe concentric wall thickening and a nondilated LV cavity, without assumed systolic anterior mitral motion or dynamic LV outflow obstruction.

An illustrative low-pitched presystolic S4 accompanies effective organized atrial contraction. AF removes this sound and the organized atrial a wave.

The numeric geometry and pressure/flow response are teaching assumptions, not measured patient data. LVH alone does not identify its cause or establish clinical HFpEF.

Step by step

  1. Reset interventions if you want the untreated example.
  2. Select the condition and inspect the pressure summary and relevant waveforms.
  3. Pause for annotations; add one intervention or loading change to compare the response.

References & further reading

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