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The Lab

Interventions

Oral treprostinil · prostacyclin analogue

Find Oral treprostinil · prostacyclin analogue in Pulmonary vasodilators. Treprostinil is a prostacyclin analogue that activates prostanoid receptors and promotes cAMP-mediated vasodilation. Extended-release oral treprostinil is distinct from the selective IP-receptor agonist selexipag and from infused treprostinil.

Overview

Open Interventions → Pulmonary vasodilators. Choose Off, Low, Medium, High. Effect levels and flow targets represent illustrative modeled responses; they are not clinical dose instructions.

Treprostinil is a prostacyclin analogue that activates prostanoid receptors and promotes cAMP-mediated vasodilation. Extended-release oral treprostinil is distinct from the selective IP-receptor agonist selexipag and from infused treprostinil.

The paused reference covers the route (Oral extended-release maintenance tablets, taken with food after individualized titration.), example doses/settings, indications, adverse effects, contraindications/precautions and monitoring. These details are available after the intervention is selected.

What to monitor in the reference: Blood pressure, tolerability, interactions, hepatic function, symptoms, biomarkers and RV/haemodynamic response; review the local label before initiation or interruption.

Step by step

  1. Inspect the untreated disease and active treatment count.
  2. Apply the intervention and compare pressures, forward flow, rhythm and congestion.
  3. Pause for its full reference; use Off or Interventions Reset to restart the comparison.

References & further reading

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