Overview
Open Interventions → Pulmonary vasodilators. Choose Off, On. Effect levels and flow targets represent illustrative modeled responses; they are not clinical dose instructions.
Sotatercept is an ActRIIA–Fc ligand trap that reduces excessive activin-related growth signaling. It is not a direct BMPR2 agonist or an acute rescue vasodilator.
The paused reference covers the route (Subcutaneous maintenance injection; the simulation illustrates a later treatment endpoint.), example doses/settings, indications, adverse effects, contraindications/precautions and monitoring. These details are available after the intervention is selected.
What to monitor in the reference: Haemoglobin/platelets before each of the first 5 doses, longer if unstable, and periodically thereafter; bleeding, blood pressure, hypersensitivity and clinical/RV response.