CIRCULATION STUDIO FIELD GUIDE
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Interventions
Every drug, maneuver, device and electrical intervention.
Sotatercept · activin inhibitor
Find Sotatercept · activin inhibitor in Pulmonary vasodilators. Sotatercept is an ActRIIA–Fc ligand trap that reduces excessive activin-related growth signaling. It is not a direct BMPR2 agonist or an acute rescue vasodilator.
Squat
Find Squat in Maneuvers. Squatting transiently increases venous return and systemic resistance. A larger LV cavity and higher afterload usually reduce dynamic LVOT obstruction and delay the MVP click; fixed regurgitation can still increase with afterload.
Stand from squat
Find Stand from squat in Maneuvers. Standing after squatting releases vascular compression and reduces venous return. The immediate BP/volume dip may provoke HOCM obstruction or an earlier MVP click; intact reflexes increase sinus rate.
Surgical tricuspid valve
Find Surgical tricuspid valve in Experimental. Surgical replacement corrects native tricuspid regurgitation or stenosis, reducing RA valve-related pressure burden. RV afterload can increase after eliminating TR.
Synchronized DCCV
Find Synchronized DCCV in Electricity. An R-wave-synchronized electrical shock interrupts susceptible tachyarrhythmia circuits while avoiding the vulnerable repolarization period.
TAVI
Find TAVI in Experimental. A transcatheter tissue valve relieves native aortic obstruction. LV systolic load falls, with a small remaining flow-dependent prosthetic gradient.
Temporary transvenous pacing
Find Temporary transvenous pacing in Electricity. Electrical ventricular capture raises ventricular rate; isolated V pacing does not restore AV synchrony.
Tricuspid clip
Find Tricuspid clip in Experimental. Leaflet approximation reduces tricuspid regurgitation and systolic RA c–v loading; a restrictive opening can impair RV filling.
V-A ECMO
Find V-A ECMO in Mechanical support. Venous drainage, extracorporeal oxygenation and arterial return support systemic perfusion. Peripheral return increases LV afterload; LV distension and pulmonary edema may require unloading.
Valsalva
Find Valsalva in Maneuvers. Forced expiration against resistance raises intrathoracic pressure. I: transient BP rise. II: reduced venous return with reflex responses. III: release-related BP dip. IV: recovery/overshoot; severe HF may blunt the usual pattern.
Vasopressin
Find Vasopressin in Vasopressors. V₁-mediated vasoconstriction independent of adrenergic receptors.